oxandrolone
structural formula
| business number | 015y |
|---|---|
| molecular formula | c19h30o3 |
| molecular weight | 306.44 |
| label |
(4as,4bs,6as,7r,9as,9br,11as)-7-hydroxy-4a,6a,7-trimethyl-tetradecahydroindeno[4,5-h]isochromene-2(1h) -ketone, (4as,4bs,6as,7r,9as,9br,11as)-7-hydroxy-4a,6a,7-trimethyl-tetradecahydroindeno[4,5-h]isochromen-2(1h)-one |
numbering system
cas number:53-39-4
mdl number:mfcd00198944
einecs number:200-172-9
rtecs number:rn6800700
brn number:none
pubchem id:none
physical property data
1. character: white odorless crystalline powder
2. density (g/ml,25/4℃): undetermined
3. relative vapor density (g/ml,air=1): undetermined
4. melting point (ºc):235-238
5. boiling point (ºc,normal pressure): undetermined
6. boiling point (ºc,5.2kpa): undetermined
7. refractive index: undetermined
8. flashpoint (ºc): undetermined
9. specific optical rotation (º): undetermined
10. autoignition point or ignition temperature (ºc): undetermined
11. vapor pressure (kpa,25ºc): undetermined
12. saturation vapor pressure (kpa,60ºc): undetermined
13. heat of combustion (kj/mol): undetermined
14. critical temperature (ºc): undetermined
15. critical pressure (kpa): undetermined
16. oil and water (octanol/log value of partition coefficient (water): undetermined
17. explosion limit (%,v/v): undetermined
18. lower explosion limit (%,v/v): undetermined
19. solubility:easily soluble in chloroform, slightly soluble in ethanol, acetone, slightly soluble in ether, and very slightly soluble in water.
toxicological data
1, acute toxicity: rat oral ld50: >10 mg/kg; rat intraperitoneal ld50 span>: 4893 mg/kg; rat subcutaneous ld50: >10 mg/kg ; mouse oral ld50: 1832 mg/kg;
mouse abdominal cavityld50: 922 mg/kg; mouse subcutaneous: >11 mg/kg; rabbit oral ld50: >5 mg/kg
2, reproductive toxicity: oral administration to female rats tdlo: 1800mg/kg, 2-19 pregnancy occurs after 3 days; subcutaneous tdlo in female rats: 70mg/kg, 14 mate in advance;
female rattdlo：300mg/kg, 30 days before mating
ecological data
none yet
molecular structure data
1. molar refractive index: 85.10
2. molar volume (m3/mol）：277.0
3. isotonic ratio(90.2k)：696.3
4. surface tension(dyne/cm)：39.8
5. polarizability(10-24cm3)：33.73
compute chemical data
1. reference value for hydrophobic parameter calculation (xlogp): 3.7
2. number of hydrogen bond donors: 1
3. number of hydrogen bond acceptors: 3
4. number of rotatable chemical bonds: 0
5. number of tautomers: 2
6. topological molecule polar surface area 46.5
7. number of heavy atoms: 22
8. surface charge: 0
9. complexity: 503
10. number of isotope atoms: 0
11. determine the number of atomic stereocenters: 7
12. uncertain number of atomic stereocenters: 0
13. determine the chemical bond stereocenter.�number: 0
14. number of uncertain chemical bond stereocenters: 0
15. number of covalent bond units: 1
properties and stability
none yet
storage method
seal and store in a cool place away from light.
synthesis method
with5-androster-1-ene–3-17-二keto or17β-hydroxy-17-α-methyl derivatives are used as raw materials.
purpose
is a male hormone whose main function is protein assimilation. used to treat high cholesterol and triglycerides.
extended-reading:https://www.bdmaee.net/nt-cat-dmcha-l-catalyst-cas10144-28-9-newtopchem/extended-reading:https://www.newtopchem.com/archives/573extended-reading:https://www.bdmaee.net/wp-content/uploads/2022/08/-bx405-low-odor-amine-catalyst-bx405–bx405-polyurethane-catalyst.pdfextended-reading:https://www.bdmaee.net/wp-content/uploads/2020/06/80-2.jpgextended-reading:https://www.cyclohexylamine.net/addocat-106-teda-l33b-dabco-polycat/extended-reading:https://www.newtopchem.com/archives/44759extended-reading:https://www.bdmaee.net/cas-26401-97-8/extended-reading:https://www.newtopchem.com/archives/44003extended-reading:https://www.bdmaee.net/pc-cat-td100-catalyst/extended-reading:https://www.newtopchem.com/archives/584
